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  • Product Name: Toddalolactone
  • Price: ￥Inquiry/5mg
  • Purity: 98.0%
  • Stocking Period: 10 Day
  • Contact: Xueping-Zheng
Related CAS#:
483-90-9 134052-25-8
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483-90-9

483-90-9 structure
483-90-9 structure
  • Name: Toddalolactone
  • Chemical Name: 6-[(2R)-2,3-dihydroxy-3-methylbutyl]-5,7-dimethoxychromen-2-one
  • CAS Number: 483-90-9
  • Molecular Formula: C16H20O6
  • Molecular Weight: 308.326
  • Catalog: Biochemical Plant extracts
  • Create Date: 2018-09-26 12:51:01
  • Modify Date: 2024-01-02 10:10:31
  • Toddalolactone, a main component of Toddalia asiatica, inhibits the activity of recombinant human plasminogen activator inhibitor-1 (PAI-1), with an IC50 value of 37.31 μM[1].
Name 6-[(2R)-2,3-dihydroxy-3-methylbutyl]-5,7-dimethoxychromen-2-one
Synonyms 2H-1-Benzopyran-2-one, 6-(2,3-dihydroxy-3-methylbutyl)-5,7-dimethoxy-
6-[(2r)-2,3-dihydroxy-3-methylbutyl]-5,7-dimethoxy-2h-chromen-2-one
6-(2,3-Dihydroxy-3-methylbutyl)-5,7-dimethoxy-2H-chromen-2-one
(+)-toddalolactone
Toddaline
Toddalolactone
Description Toddalolactone, a main component of Toddalia asiatica, inhibits the activity of recombinant human plasminogen activator inhibitor-1 (PAI-1), with an IC50 value of 37.31 μM[1].
Related Catalog
In Vitro Toddalolactone, a natural coumarin, inhibits PAI-1 activity by preventing the formation of a stable PAI-1/uPA covalent complex, suggesting that the inhibitory effect of Toddalolactone may be due to the interference of close contact between plasminogen activator and the active center of PAI-1[1].
References

[1]. Yu B, et al. Inhibition of PAI-1 Activity by Toddalolactone as a Mechanism for Promoting Blood Circulation and Removing Stasis by Chinese Herb Zanthoxylum nitidum var. tomentosum. Front Pharmacol. 2017 Jul 21;8:489.
Density 1.3±0.1 g/cm3
Boiling Point 530.0±50.0 °C at 760 mmHg
Molecular Formula C16H20O6
Molecular Weight 308.326
Flash Point 195.5±23.6 °C
Exact Mass 308.125977
PSA 89.13000
LogP 0.88
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.569
Storage condition 2-8C
137764-14-8 structure

137764-14-8

~15%

77636-08-9 structure

77636-08-9

483-90-9 structure

483-90-9

Literature: Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 13 p. 1681 - 1684
Precursor  1

DownStream  0


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title: CAS No. 483-90-9 | Chemsrc address: https://m.chemsrc.com/en/baike/165442.html

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