DC Chemicals Limited
China
Product Name: 7-Dehydrocholesterol
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Purity: 98.0%
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 7-Dehydrocholesterol
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Purity: 98.0%
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Zhejiang Hangyu API Co., Ltd
China
Product Name: 7-Dehydrocholesterol
Price: ￥Inquiry/1kg
Purity: 99.5%
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Henan Tianfu Chemical Co., Ltd.
China
Product Name: cholesta-5,7-dien-3β-ol
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

434-16-2

434-16-2 structure

434-16-2 structure

Name: (3β)-7-Dehydro Cholesterol
Chemical Name: cholesta-5,7-dien-3β-ol
CAS Number: 434-16-2
Molecular Formula: C₂₇H₄₄O
Molecular Weight: 384.638
Catalog: Chemical reagent Organic reagent Fatty alcohol
Create Date: 2018-05-23 08:00:00
Modify Date: 2024-01-02 19:39:34
7-Dehydrocholesterol is biosynthetic precursor of cholesterol and vitamin D3.

Name	cholesta-5,7-dien-3β-ol
Synonyms	delta7-Cholesterol (3b)-7-Dehydrocholesterol Cholesta-5,7-dien-3-ol, (3β)- Cholesta-5,7-dien-3β-ol (8CI) Cholesta-5,7-dien-3-β-ol Provitamin D3 EINECS 207-100-5 Dehydrocholesterol (3Beta)-7-Dehydro Cholesterol (3b)-Cholesta-5,7-dien-3-ol 3β-Hydroxy-5,7-cholestadiene Provitamine cholesta-5,7-dien-3beta-ol (-)-7-dehydrocholesterol Dehydrocholesterin (3β)-Cholesta-5,7-dien-3-ol 5,7-Cholestadien-3β-ol 7-DHC 7-Dehydrocholesterol Provitamin D(sub 3) MFCD00003624 Cholesta-5,7-dien-3β-ol cholesta-5,7-dien-3b-ol (3β)-7-Dehydrocholesterol

Description	7-Dehydrocholesterol is biosynthetic precursor of cholesterol and vitamin D3.
Related Catalog	Natural Products >> Steroids Research Areas >> Others
Target	Human Endogenous Metabolite
In Vitro	7-Dehydrocholesterol is a biosynthetic precursor of cholesterol and vitamin D3. 7-Dehydrocholesterol is present in relatively high concentration in skin where it is converted to pre-vitamin D3 upon UV irradiation and where it is also exposed to exogenous radical sources and oxygen[1].
References	[1]. Xu L, et al. Oxysterols from free radical chain oxidation of 7-dehydrocholesterol: product and mechanistic studies. J Am Chem Soc. 2010 Feb 24;132(7):2222-32.

Density	1.0±0.1 g/cm3
Boiling Point	493.7±34.0 °C at 760 mmHg
Melting Point	148-152 °C(lit.)
Molecular Formula	C₂₇H₄₄O
Molecular Weight	384.638
Flash Point	212.3±17.9 °C
Exact Mass	384.339203
PSA	20.23000
LogP	9.46
Vapour Pressure	0.0±2.8 mmHg at 25°C
Index of Refraction	1.536
Storage condition	-20℃

CHEMICAL IDENTIFICATION

RTECS NUMBER :: FZ5650000

CHEMICAL NAME :: Cholesta-5,7-dien-3-beta-ol

CAS REGISTRY NUMBER :: 434-16-2

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C27-H44-O

MOLECULAR WEIGHT :: 384.71

WISWESSER LINE NOTATION :: L E5 B666 JU LUTJ A1 E1 FY1&3Y1&1 OQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 60 gm/kg/2W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Tumorigenic - tumors at site of application

REFERENCE :: NATWAY Naturwissenschaften. (Springer-Verlag, Heidelberger Platz 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.1- 1913- Volume(issue)/page/year: 60,525,1973

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases	S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	FZ5650000

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