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1747-60-0

1747-60-0 structure
1747-60-0 structure

Name 2-Amino-6-methoxybenzothiazole
Synonyms 2-Amino-6-methoxybenzothiazole
6-Methoxy-1,3-benzothiazol-2-amine
6-Methoxy-2-aminobenzothiazole
2-Benzothiazolamine, 6-methoxy-
EINECS 217-130-0
MFCD00005787
Density 1.4±0.1 g/cm3
Boiling Point 347.5±34.0 °C at 760 mmHg
Melting Point 165-167 °C(lit.)
Molecular Formula C8H8N2OS
Molecular Weight 180.227
Flash Point 163.9±25.7 °C
Exact Mass 180.035736
PSA 76.38000
LogP 1.81
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.705
Stability Stable, but may be light sensitive. Incompatible with strong oxidizing agents.
Water Solubility <0.1 g/100 mL at 21 ºC

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DL2100000
CHEMICAL NAME :
Benzothiazole, 2-amino-6-methoxy-
CAS REGISTRY NUMBER :
1747-60-0
BEILSTEIN REFERENCE NO. :
0131202
LAST UPDATED :
199701
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C8-H8-N2-O-S
MOLECULAR WEIGHT :
180.24
WISWESSER LINE NOTATION :
T56 BN DSJ CZ GO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
140 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Unscheduled DNA synthesis
TEST SYSTEM :
Rodent - rat Liver
DOSE/DURATION :
10 umol/L
REFERENCE :
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 3,11,1981
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn,Xi
Risk Phrases R22:Harmful if swallowed. R36/37/38:Irritating to eyes, respiratory system and skin . R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
Safety Phrases S26
RIDADR 2811
WGK Germany 3
RTECS DL2100000
HS Code 2934999090

~95%

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Literature: Synlett, , vol. 23, # 15 p. 2219 - 2222

~94%

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Literature: Synlett, , # 19 p. 2952 - 2956

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Literature: Helvetica Chimica Acta, , vol. 63, # 3 p. 682 - 692

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Literature: Synthesis, , # 7 p. 970 - 974

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Literature: Research on Chemical Intermediates, , vol. 36, # 8 p. 985 - 993

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Literature: Biological and Pharmaceutical Bulletin, , vol. 25, # 3 p. 335 - 341

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Literature: Medicinal Chemistry Research, , vol. 22, # 1 p. 195 - 210

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1747-60-0

Literature: Bulletin de la Societe Chimique de France, , p. 684,688

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Literature: Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 27, # 1-12 p. 189 - 190
HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%