2-Amino-6-methoxybenzothiazole

Modify Date: 2024-01-02 07:32:27

2-Amino-6-methoxybenzothiazole structure	Common Name	2-Amino-6-methoxybenzothiazole
	CAS Number	1747-60-0	Molecular Weight	180.227
	Density	1.4±0.1 g/cm3	Boiling Point	347.5±34.0 °C at 760 mmHg
	Molecular Formula	C₈H₈N₂OS	Melting Point	165-167 °C(lit.)
	MSDS	Chinese USA	Flash Point	163.9±25.7 °C
	Symbol	GHS07	Signal Word	Warning

Name	2-Amino-6-methoxybenzothiazole
Synonym	More Synonyms

Density	1.4±0.1 g/cm3
Boiling Point	347.5±34.0 °C at 760 mmHg
Melting Point	165-167 °C(lit.)
Molecular Formula	C₈H₈N₂OS
Molecular Weight	180.227
Flash Point	163.9±25.7 °C
Exact Mass	180.035736
PSA	76.38000
LogP	1.81
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.705
Stability	Stable, but may be light sensitive. Incompatible with strong oxidizing agents.
Water Solubility	<0.1 g/100 mL at 21 ºC

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DL2100000

CHEMICAL NAME :: Benzothiazole, 2-amino-6-methoxy-

CAS REGISTRY NUMBER :: 1747-60-0

BEILSTEIN REFERENCE NO. :: 0131202

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C8-H8-N2-O-S

MOLECULAR WEIGHT :: 180.24

WISWESSER LINE NOTATION :: T56 BN DSJ CZ GO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 140 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Unscheduled DNA synthesis

TEST SYSTEM :: Rodent - rat Liver

DOSE/DURATION :: 10 umol/L

REFERENCE :: ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 3,11,1981

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn,Xi
Risk Phrases	R22:Harmful if swallowed. R36/37/38:Irritating to eyes, respiratory system and skin . R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
Safety Phrases	S26
RIDADR	2811
WGK Germany	3
RTECS	DL2100000
HS Code	2934999090

Potassium thioc...

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p-Anisidine

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~95%

2-Amino-6-metho...

CAS#:1747-60-0

Literature: Synlett, , vol. 23, # 15 p. 2219 - 2222

ammonium;thiocyanate

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p-Anisidine

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~94%

2-Amino-6-metho...

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Literature: Synlett, , # 19 p. 2952 - 2956

4-methoxyphenyl...

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~91%

2-Amino-6-metho...

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Literature: Helvetica Chimica Acta, , vol. 63, # 3 p. 682 - 692

Sodium thiocyanate

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p-Anisidine

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~62%

2-Amino-6-metho...

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Literature: Synthesis, , # 7 p. 970 - 974

p-Anisidine

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2-Amino-6-metho...

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Literature: Research on Chemical Intermediates, , vol. 36, # 8 p. 985 - 993

p-anisidine hyd...

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2-Amino-6-metho...

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6-methoxybenzo[...

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4-methoxyphenyl...

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2-Amino-6-metho...

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5-Bromo-6-Metho...

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Cuprous thiocyanate

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p-Anisidine

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2-Amino-6-metho...

CAS#:1747-60-0

Literature: Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 27, # 1-12 p. 189 - 190

Precursor 6
CAS#:333-20-0 Potassium thioc... CAS#:104-94-9 p-Anisidine CAS#:2293-07-4 4-methoxyphenyl... CAS#:540-72-7 Sodium thiocyanate
CAS#:20265-97-8 p-anisidine hyd... CAS#:1111-67-7 Cuprous thiocyanate
DownStream 10
CAS#:10205-69-3 6-methoxy-2-phe... CAS#:3427-30-3 2-CHLORO-N-(6-M... CAS#:40925-65-3 6-Methoxy-2(3H)... CAS#:14372-79-3 Thiocyanic acid...
CAS#:94-45-1 2-Amino-6-ethox... CAS#:939-69-5 2-CYANO-6-HYDRO... CAS#:943-03-3 2-Cyano-6-metho... CAS#:20174-70-3 2-Hydrazino-6-m...
CAS#:2605-14-3 2-Chloro-6-meth... CAS#:808755-67-1 2-BROMOBENZOTHI...

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synthesis and antimicrobial activity of new 4-thiazolidinone derivatives containing 2-amino-6-methoxybenzothiazole.

Saudi Pharm. J. 18(3) , 129-36, (2010)

A novel series of Schiff bases 5a-j and 4-thiazolidinones 6a-j have been prepared from the building blocks 2-chloro pyridine-3-carboxylic acid [1] and 2-amino-6-methoxy-benzothiazole [2]. All of the s...

Effect of Aroclor 1254 dose upon S9 activation of aromatic amine bacterial mutagens.

Mutat. Res. 77(4) , 361-6, (1980)

Structural, vibrational, electronic investigations and quantum chemical studies of 2-amino-4-methoxybenzothiazole.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 102 , 327-40, (2013)

Extensive vibrational investigations of 2-amino-4-methoxybenzothiazole have been carried out with FTIR and FT-Raman spectral techniques. The electronic structure of the molecule has been analysed by U...

2-Amino-6-methoxybenzothiazole

6-Methoxy-1,3-benzothiazol-2-amine

6-Methoxy-2-aminobenzothiazole

2-Benzothiazolamine, 6-methoxy-

EINECS 217-130-0

MFCD00005787