166108-71-0

166108-71-0 structure

Name: Fmoc-8-amino-3,6-dioxaoctanoic acid
Chemical Name: [2-[2-(Fmoc-amino)ethoxy]ethoxy]acetic acid
CAS Number: 166108-71-0
Molecular Formula: C₂₁H₂₃NO₆
Molecular Weight: 385.410
Catalog: Biochemical Amino acids and their derivatives FMOC-amino acid
Create Date: 2018-12-16 20:50:15
Modify Date: 2024-01-02 18:50:42
Fmoc-8-amino-3,6-dioxaoctanoic acid (Fmoc-NH-PEG2-CH2COOH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name	[2-[2-(Fmoc-amino)ethoxy]ethoxy]acetic acid
Synonyms	2,7,10-Trioxa-4-azadodecan-12-oic acid, 1-(9H-fluoren-9-yl)-3-oxo- [2-[2-(Fmoc-Amino)ethoxy]ethoxy]acetic acid [2-[2-[(Fmoc-amino)ethoxy]ethoxy]acetic Acid 8-(Fmoc-amino)-3,6-dioxa-n-octanoic Acid {2-[2-(9H-Fluoren-9-ylmethoxycarbonylamino)-ethoxy]-ethoxy}-acetic acid Fmoc-NH-PEG2-CH2COOH MFCD01321015 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10-trioxa-4-azadodecan-12-oic acid [2-[2-[(9H-Fluoren-9-ylmethoxy)carbonylamino]ethoxy]ethoxy]acetic Acid 2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]acetic acid 8-[(9H-Fluoren-9-ylMethoxy)carbonylaMino]-3,6-dioxa-n-octanoic Acid Fmoc-mini-PEG Fmoc-AEEA

Description	Fmoc-8-amino-3,6-dioxaoctanoic acid (Fmoc-NH-PEG2-CH2COOH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References	[1]. Nakamura A, et al. Chemogenetic Control of Protein Anchoring to Endomembranes in Living Cells with Lipid-Tethered Small Molecules. Biochemistry. 2020 Jan 21;59(2):205-211.