560088-66-6

560088-66-6 structure
560088-66-6 structure
  • Name: Fmoc-PEG3-alcohol
  • Chemical Name: 9H-fluoren-9-ylmethyl N-[2-[2-(2-hydroxyethoxy)ethoxy]ethyl]carbamate
  • CAS Number: 560088-66-6
  • Molecular Formula: C21H25NO5
  • Molecular Weight: 371.42700
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2016-11-21 17:35:35
  • Modify Date: 2024-01-03 10:44:15
  • Fmoc-PEG3-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 9H-fluoren-9-ylmethyl N-[2-[2-(2-hydroxyethoxy)ethoxy]ethyl]carbamate
Synonyms og002
Description Fmoc-PEG3-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

Density 1.208g/cm3
Boiling Point 581.5ºC at 760 mmHg
Molecular Formula C21H25NO5
Molecular Weight 371.42700
Flash Point 305.5ºC
Exact Mass 371.17300
PSA 77.02000
LogP 2.94150
Index of Refraction 1.572