144060-98-0
144060-98-0 structure
- Name: 4-methyl-2-pyrid-4-yl-1,3-thiazole-5-carboxylic acid
- Chemical Name: 4-methyl-2-pyridin-4-yl-1,3-thiazole-5-carboxylic acid
- CAS Number: 144060-98-0
- Molecular Formula: C10H8N2O2S
- Molecular Weight: 220.248
- Catalog: Pharmaceutical intermediate Heterocyclic compound Pyridine compound Pyridine derivative
- Create Date: 2018-12-25 12:08:34
- Modify Date: 2024-01-04 23:03:34
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2-(4-pyridyl)-4-methyl-Thiazole-5-carboxylic acid is a synthetic intermediate useful for pharmaceutical synthesis.
| Name | 4-methyl-2-pyridin-4-yl-1,3-thiazole-5-carboxylic acid |
|---|---|
| Synonyms |
4-methyl-2-(pyridin-4-yl)-1,3-thiazole-5-carboxylic acid
4-Methyl-2-(4-pyridinyl)-5-thiazolecarboxylic acid 4-Methyl-2-(pyridin-4-yl)thiazole-5-carboxylic acid 4-Methyl-2-(4-pyridinyl)-1,3-thiazole-5-carboxylic acid 4-methyl-2-(4-pyridyl)-1,3-thiazole-5-carboxylic acid 5-Thiazolecarboxylic acid, 4-methyl-2-(4-pyridinyl)- 4-methyl-2-(4-pyridyl)thiazole-5-carboxylic acid |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 467.0±55.0 °C at 760 mmHg |
| Melting Point | 254.5ºC |
| Molecular Formula | C10H8N2O2S |
| Molecular Weight | 220.248 |
| Flash Point | 236.3±31.5 °C |
| Exact Mass | 220.030655 |
| PSA | 91.32000 |
| LogP | 2.12 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.636 |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H319 |
| Precautionary Statements | P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | R36 |
| Safety Phrases | 26 |
| RIDADR | NONH for all modes of transport |
| HS Code | 2934100090 |
|
~87%
144060-98-0 |
| Literature: Takeda Chemical Industries, Ltd. Patent: US6359134 B1, 2002 ; Location in patent: Referential example 21 ; US 6359134 B1 |
| Precursor 1 | |
|---|---|
| DownStream 0 | |
| HS Code | 2934100090 |
|---|---|
| Summary | 2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0% |