4-methyl-2-pyrid-4-yl-1,3-thiazole-5-carboxylic acid

Modify Date: 2024-01-04 23:03:34

4-methyl-2-pyrid-4-yl-1,3-thiazole-5-carboxylic acid Structure
4-methyl-2-pyrid-4-yl-1,3-thiazole-5-carboxylic acid structure
Common Name 4-methyl-2-pyrid-4-yl-1,3-thiazole-5-carboxylic acid
CAS Number 144060-98-0 Molecular Weight 220.248
Density 1.4±0.1 g/cm3 Boiling Point 467.0±55.0 °C at 760 mmHg
Molecular Formula C10H8N2O2S Melting Point 254.5ºC
MSDS Chinese USA Flash Point 236.3±31.5 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of 4-methyl-2-pyrid-4-yl-1,3-thiazole-5-carboxylic acid


2-(4-pyridyl)-4-methyl-Thiazole-5-carboxylic acid is a synthetic intermediate useful for pharmaceutical synthesis.

 Names

Name 4-methyl-2-pyridin-4-yl-1,3-thiazole-5-carboxylic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 467.0±55.0 °C at 760 mmHg
Melting Point 254.5ºC
Molecular Formula C10H8N2O2S
Molecular Weight 220.248
Flash Point 236.3±31.5 °C
Exact Mass 220.030655
PSA 91.32000
LogP 2.12
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.636

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H319
Precautionary Statements P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36
Safety Phrases 26
RIDADR NONH for all modes of transport
HS Code 2934100090

 Synthetic Route

~87%

4-methyl-2-pyrid-4-yl-1,3-thiazole-5-carboxylic acid Structure

4-methyl-2-pyri...

CAS#:144060-98-0

Literature: Takeda Chemical Industries, Ltd. Patent: US6359134 B1, 2002 ; Location in patent: Referential example 21 ; US 6359134 B1

 Precursor & DownStream

Precursor  1

DownStream  0

 Customs

HS Code 2934100090
Summary 2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

 Synonyms

4-methyl-2-(pyridin-4-yl)-1,3-thiazole-5-carboxylic acid
4-Methyl-2-(4-pyridinyl)-5-thiazolecarboxylic acid
4-Methyl-2-(pyridin-4-yl)thiazole-5-carboxylic acid
4-Methyl-2-(4-pyridinyl)-1,3-thiazole-5-carboxylic acid
4-methyl-2-(4-pyridyl)-1,3-thiazole-5-carboxylic acid
5-Thiazolecarboxylic acid, 4-methyl-2-(4-pyridinyl)-
4-methyl-2-(4-pyridyl)thiazole-5-carboxylic acid