371924-24-2
371924-24-2 structure
- Name: MCU-i4
- Chemical Name: MCU-i4
- CAS Number: 371924-24-2
- Molecular Formula: C23H27N3O2
- Molecular Weight: 377.48
- Catalog: Research Areas Metabolic Disease
- Create Date: 2021-09-12 18:14:45
- Modify Date: 2024-01-11 21:25:08
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MCU-i4 blocks the IP3-dependent mitochondrial Ca2+-uptake, maintaining the gatekeeping role of their target[1][2].
| Name | MCU-i4 |
|---|---|
| Synonyms | MFCD02730422 |
| Description | MCU-i4 blocks the IP3-dependent mitochondrial Ca2+-uptake, maintaining the gatekeeping role of their target[1][2]. |
|---|---|
| Related Catalog | |
| In Vitro | MCU-i4 modulates mitochondrial Ca2+ uptake to 1 min of incubation, i.e., exerting a negative modulation, indicating that the primary effect of these compounds is a sudden and direct modulation of MCU complex activity[1]. MCU-i4 exerted a negative effect on Δψ. MCU-i4 has no effect on cell viability[1]. Cell Differentiation Assay[1] Cell Line: Growing medium of 90% confluent C2C12 myoblasts. Concentration: 10 μM. Incubation Time: 24 h. Result: Decreased myotube width. |
| References |
| Molecular Formula | C23H27N3O2 |
|---|---|
| Molecular Weight | 377.48 |