MCU-i4
Modify Date: 2025-08-25 19:28:48
MCU-i4 structure
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Common Name | MCU-i4 | ||
|---|---|---|---|---|
| CAS Number | 371924-24-2 | Molecular Weight | 377.48 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H27N3O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of MCU-i4MCU-i4 blocks the IP3-dependent mitochondrial Ca2+-uptake, maintaining the gatekeeping role of their target[1][2]. |
| Name | MCU-i4 |
|---|---|
| Synonym | More Synonyms |
| Description | MCU-i4 blocks the IP3-dependent mitochondrial Ca2+-uptake, maintaining the gatekeeping role of their target[1][2]. |
|---|---|
| Related Catalog | |
| In Vitro | MCU-i4 modulates mitochondrial Ca2+ uptake to 1 min of incubation, i.e., exerting a negative modulation, indicating that the primary effect of these compounds is a sudden and direct modulation of MCU complex activity[1]. MCU-i4 exerted a negative effect on Δψ. MCU-i4 has no effect on cell viability[1]. Cell Differentiation Assay[1] Cell Line: Growing medium of 90% confluent C2C12 myoblasts. Concentration: 10 μM. Incubation Time: 24 h. Result: Decreased myotube width. |
| References |
| Molecular Formula | C23H27N3O2 |
|---|---|
| Molecular Weight | 377.48 |
| InChIKey | RIWXBJCWHVMATR-UHFFFAOYSA-N |
| SMILES | CCOC(=O)c1cnc2ccc(C)cc2c1Nc1ccc(N(CC)CC)cc1 |
| MFCD02730422 |