1621884-18-1

1621884-18-1 structure

Name: AT-9010 tetrasodium
Chemical Name: AT-9010 tetrasodium
CAS Number: 1621884-18-1
Molecular Formula: C₁₁H₁₃FN₅Na₄O₁₃P₃
Molecular Weight: 627.13
Catalog: Signaling Pathways Anti-infection SARS-CoV
Create Date: 2021-09-16 11:24:45
Modify Date: 2025-08-27 09:47:24
AT-9010 tetrasodium, a triphosphate active metabolite of AT-527, is a potent inhibitor of NiRAN (a function essential for viral replication). AT-9010 tetrasodium can inhibit SARS-CoV-2 replication[1].

Name	AT-9010 tetrasodium

Description	AT-9010 tetrasodium, a triphosphate active metabolite of AT-527, is a potent inhibitor of NiRAN (a function essential for viral replication). AT-9010 tetrasodium can inhibit SARS-CoV-2 replication[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> SARS-CoV
Target	NiRAN[1]
In Vitro	Substantial levels of the active triphosphate metabolite AT-9010 are formed in normal human bronchial and nasal epithelial cells incubated with 10 µM AT-511 (698 µM and 236 µM, respectively), with a half-life of at least 38 hours[1].
References	[1]. Atea Pharmaceuticals Announces Publication of Preclinical Data Highlighting Potent Activity of AT-527 Against SARS-CoV-2. BOSTON, Feb. 08, 2021. Atea Pharmaceuticals, Inc.

Molecular Formula	C₁₁H₁₃FN₅Na₄O₁₃P₃
Molecular Weight	627.13

Hazard Codes	Xi