1087243-14-8
1087243-14-8 structure
- Name: GRL-0496
- Chemical Name: GRL-0496
- CAS Number: 1087243-14-8
- Molecular Formula: C14H9ClN2O2
- Molecular Weight: 272.69
- Catalog: Signaling Pathways Anti-infection SARS-CoV
- Create Date: 2021-09-11 19:50:48
- Modify Date: 2024-01-05 10:37:56
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GRL-0496 is a potent chloropyridyl ester-derived SARS-CoV 3CLpro inhibitor, with an IC50 of 30 nM in both enzyme inhibitory and antiviral assays. GRL-0496 shows SARS-CoV antiviral activity, with an EC50 of 6.9 μM[1].
| Name | GRL-0496 |
|---|
| Description | GRL-0496 is a potent chloropyridyl ester-derived SARS-CoV 3CLpro inhibitor, with an IC50 of 30 nM in both enzyme inhibitory and antiviral assays. GRL-0496 shows SARS-CoV antiviral activity, with an EC50 of 6.9 μM[1]. |
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| Related Catalog | |
| Target |
IC50: 30 nM (SARS-CoV 3CLpro)[1] |
| In Vitro | GRL-0496 shows the best SARS-CoV antiviral activity, with an EC EC50 of 6.9 μM[1]. |
| References |
| Molecular Formula | C14H9ClN2O2 |
|---|---|
| Molecular Weight | 272.69 |