GRL-0496

Modify Date: 2024-01-05 10:37:56

GRL-0496 structure	Common Name	GRL-0496
	CAS Number	1087243-14-8	Molecular Weight	272.69
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₄H₉ClN₂O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of GRL-0496

GRL-0496 is a potent chloropyridyl ester-derived SARS-CoV 3CLpro inhibitor, with an IC50 of 30 nM in both enzyme inhibitory and antiviral assays. GRL-0496 shows SARS-CoV antiviral activity, with an EC50 of 6.9 μM[1].

Name	GRL-0496

Description	GRL-0496 is a potent chloropyridyl ester-derived SARS-CoV 3CLpro inhibitor, with an IC50 of 30 nM in both enzyme inhibitory and antiviral assays. GRL-0496 shows SARS-CoV antiviral activity, with an EC50 of 6.9 μM[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> SARS-CoV
Target	IC50: 30 nM (SARS-CoV 3CLpro)[1]
In Vitro	GRL-0496 shows the best SARS-CoV antiviral activity, with an EC EC50 of 6.9 μM[1].
References	[1]. Ghosh AK, et, al. Design, synthesis and antiviral efficacy of a series of potent chloropyridyl ester-derived SARS-CoV 3CLpro inhibitors. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5684-8.

Molecular Formula	C₁₄H₉ClN₂O₂
Molecular Weight	272.69

DC Chemicals Limited
China
Product Name: GRL-0496
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Cao

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