1620160-42-0
1620160-42-0 structure
- Name: Honokiol DCA
- Chemical Name: Honokiol DCA
- CAS Number: 1620160-42-0
- Molecular Formula: C22H18Cl4O4
- Molecular Weight: 488.19
- Catalog: Research Areas Cancer
- Create Date: 2021-09-11 17:26:20
- Modify Date: 2024-01-11 17:33:59
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Honokiol DCA (Honokiol dichloroacetate) is a dichloroacetate analog of Honokiol. Honokiol DCA can inhibit the growth of human prostate cancer cells in vitro and suppress the androgen receptor (AR) protein level[1].
| Name | Honokiol DCA |
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| Description | Honokiol DCA (Honokiol dichloroacetate) is a dichloroacetate analog of Honokiol. Honokiol DCA can inhibit the growth of human prostate cancer cells in vitro and suppress the androgen receptor (AR) protein level[1]. |
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| Related Catalog | |
| In Vitro | Honokiol DCA (20-40 μM; 24-48 h) inhibits the viability of LNCaP and C4-2 cells in a dose-and time-dependent manner[1]. Honokiol DCA (5-20 μM; 10 days) inhibits clonogenicity of prostate cancer cells[1]. Honokiol DCA (20-40 μM; 24-48 h) significantly decreases the level of androgen receptor (AR) and prostate specific antigen (PSA) protein in LNCaP cells[1]. Honokiol DCA (40 μM; 24 h) significantly decreases AR promoter activity in LNCaP and C4-2 cells[1]. |
| In Vivo | Honokiol类似物 |
| References |
| Molecular Formula | C22H18Cl4O4 |
|---|---|
| Molecular Weight | 488.19 |