Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Honokiol DCA
Price: Check
Purity: 95.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Honokiol DCA
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

1620160-42-0

1620160-42-0 structure

1620160-42-0 structure

Name: Honokiol DCA
Chemical Name: Honokiol DCA
CAS Number: 1620160-42-0
Molecular Formula: C₂₂H₁₈Cl₄O₄
Molecular Weight: 488.19
Catalog: Research Areas Cancer
Create Date: 2021-09-11 17:26:20
Modify Date: 2025-08-25 18:52:57
Honokiol DCA (Honokiol dichloroacetate) is a dichloroacetate analog of Honokiol. Honokiol DCA can inhibit the growth of human prostate cancer cells in vitro and suppress the androgen receptor (AR) protein level[1].

Name	Honokiol DCA

Description	Honokiol DCA (Honokiol dichloroacetate) is a dichloroacetate analog of Honokiol. Honokiol DCA can inhibit the growth of human prostate cancer cells in vitro and suppress the androgen receptor (AR) protein level[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Androgen Receptor
In Vitro	Honokiol DCA (20-40 μM; 24-48 h) inhibits the viability of LNCaP and C4-2 cells in a dose-and time-dependent manner[1]. Honokiol DCA (5-20 μM; 10 days) inhibits clonogenicity of prostate cancer cells[1]. Honokiol DCA (20-40 μM; 24-48 h) significantly decreases the level of androgen receptor (AR) and prostate specific antigen (PSA) protein in LNCaP cells[1]. Honokiol DCA (40 μM; 24 h) significantly decreases AR promoter activity in LNCaP and C4-2 cells[1].
In Vivo	Honokiol类似物
References	[1]. Hahm ER, et, al. Honokiol inhibits androgen receptor activity in prostate cancer cells. Prostate. 2014 Apr;74(4):408-20.

Molecular Formula	C₂₂H₁₈Cl₄O₄
Molecular Weight	488.19

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