Honokiol DCA
Modify Date: 2024-01-11 17:33:59
Honokiol DCA structure
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Common Name | Honokiol DCA | ||
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| CAS Number | 1620160-42-0 | Molecular Weight | 488.19 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H18Cl4O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Honokiol DCAHonokiol DCA (Honokiol dichloroacetate) is a dichloroacetate analog of Honokiol. Honokiol DCA can inhibit the growth of human prostate cancer cells in vitro and suppress the androgen receptor (AR) protein level[1]. |
| Name | Honokiol DCA |
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| Description | Honokiol DCA (Honokiol dichloroacetate) is a dichloroacetate analog of Honokiol. Honokiol DCA can inhibit the growth of human prostate cancer cells in vitro and suppress the androgen receptor (AR) protein level[1]. |
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| Related Catalog | |
| In Vitro | Honokiol DCA (20-40 μM; 24-48 h) inhibits the viability of LNCaP and C4-2 cells in a dose-and time-dependent manner[1]. Honokiol DCA (5-20 μM; 10 days) inhibits clonogenicity of prostate cancer cells[1]. Honokiol DCA (20-40 μM; 24-48 h) significantly decreases the level of androgen receptor (AR) and prostate specific antigen (PSA) protein in LNCaP cells[1]. Honokiol DCA (40 μM; 24 h) significantly decreases AR promoter activity in LNCaP and C4-2 cells[1]. |
| In Vivo | Honokiol类似物 |
| References |
| Molecular Formula | C22H18Cl4O4 |
|---|---|
| Molecular Weight | 488.19 |