Honokiol DCA

Modify Date: 2025-08-25 18:52:57

Honokiol DCA Structure
Honokiol DCA structure
Common Name Honokiol DCA
CAS Number 1620160-42-0 Molecular Weight 488.19
Density N/A Boiling Point N/A
Molecular Formula C22H18Cl4O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Honokiol DCA


Honokiol DCA (Honokiol dichloroacetate) is a dichloroacetate analog of Honokiol. Honokiol DCA can inhibit the growth of human prostate cancer cells in vitro and suppress the androgen receptor (AR) protein level[1].

 Names

Name Honokiol DCA

 Honokiol DCA Biological Activity

Description Honokiol DCA (Honokiol dichloroacetate) is a dichloroacetate analog of Honokiol. Honokiol DCA can inhibit the growth of human prostate cancer cells in vitro and suppress the androgen receptor (AR) protein level[1].
Related Catalog
In Vitro Honokiol DCA (20-40 μM; 24-48 h) inhibits the viability of LNCaP and C4-2 cells in a dose-and time-dependent manner[1]. Honokiol DCA (5-20 μM; 10 days) inhibits clonogenicity of prostate cancer cells[1]. Honokiol DCA (20-40 μM; 24-48 h) significantly decreases the level of androgen receptor (AR) and prostate specific antigen (PSA) protein in LNCaP cells[1]. Honokiol DCA (40 μM; 24 h) significantly decreases AR promoter activity in LNCaP and C4-2 cells[1].
In Vivo Honokiol类似物
References

[1]. Hahm ER, et, al. Honokiol inhibits androgen receptor activity in prostate cancer cells. Prostate. 2014 Apr;74(4):408-20.

 Chemical & Physical Properties

Molecular Formula C22H18Cl4O4
Molecular Weight 488.19
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