742064-38-6

742064-38-6 structure

Name: LB-60-OF61 hydrochloride
Chemical Name: LB-60-OF61 hydrochloride
CAS Number: 742064-38-6
Molecular Formula: C₂₉H₃₁ClN₆O₂
Molecular Weight: 531.05
Catalog: Signaling Pathways Metabolic Enzyme/Protease Nampt
Create Date: 2021-09-10 06:54:00
Modify Date: 2024-02-03 11:25:33
LB-60-OF61 hydrochloride is a potent NAMPT (nicotinamide phosphoribosyltransferase) inhibitor. LB-60-OF61 hydrochloride is a cytotoxic compound with a selectivity towards MYC overexpressing cell lines[1].

Name	LB-60-OF61 hydrochloride

Description	LB-60-OF61 hydrochloride is a potent NAMPT (nicotinamide phosphoribosyltransferase) inhibitor. LB-60-OF61 hydrochloride is a cytotoxic compound with a selectivity towards MYC overexpressing cell lines[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Nampt
In Vitro	LB-60-OF61 is potent against HCT116 cells with an IC50 around 30 nM as measured in a 384 well format[1].
References	[1]. Estoppey D, et al. Identification of a novel NAMPT inhibitor by CRISPR/Cas9 chemogenomic profiling in mammalian cells. Sci Rep. 2017;7:42728. Published 2017 Feb 16.

Molecular Formula	C₂₉H₃₁ClN₆O₂
Molecular Weight	531.05