LB-60-OF61 hydrochloride

Modify Date: 2024-02-03 11:25:33

LB-60-OF61 hydrochloride Structure
LB-60-OF61 hydrochloride structure
Common Name LB-60-OF61 hydrochloride
CAS Number 742064-38-6 Molecular Weight 531.05
Density N/A Boiling Point N/A
Molecular Formula C29H31ClN6O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of LB-60-OF61 hydrochloride


LB-60-OF61 hydrochloride is a potent NAMPT (nicotinamide phosphoribosyltransferase) inhibitor. LB-60-OF61 hydrochloride is a cytotoxic compound with a selectivity towards MYC overexpressing cell lines[1].

 Names

Name LB-60-OF61 hydrochloride

 LB-60-OF61 hydrochloride Biological Activity

Description LB-60-OF61 hydrochloride is a potent NAMPT (nicotinamide phosphoribosyltransferase) inhibitor. LB-60-OF61 hydrochloride is a cytotoxic compound with a selectivity towards MYC overexpressing cell lines[1].
Related Catalog
In Vitro LB-60-OF61 is potent against HCT116 cells with an IC50 around 30 nM as measured in a 384 well format[1].
References

[1]. Estoppey D, et al. Identification of a novel NAMPT inhibitor by CRISPR/Cas9 chemogenomic profiling in mammalian cells. Sci Rep. 2017;7:42728. Published 2017 Feb 16.

 Chemical & Physical Properties

Molecular Formula C29H31ClN6O2
Molecular Weight 531.05
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