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1280215-91-9

1280215-91-9 structure
1280215-91-9 structure
  • Name: Lys-Nε-SPDB-DM4
  • Chemical Name: Lys-Nε-SPDB-DM4
  • CAS Number: 1280215-91-9
  • Molecular Formula: C48H72ClN5O13S2
  • Molecular Weight: 1026.69
  • Catalog: Research Areas Cancer
  • Create Date: 2021-09-12 20:07:04
  • Modify Date: 2023-01-17 11:32:03
  • Lys-Nε-SPDB-DM4 is a drug-linker conjugate composed of a potent a tubulin inhibitor DM4 and a linker Lys-Nε-SPDB to make antibody drug conjugate (ADC)[1].

Name Lys-Nε-SPDB-DM4
Description Lys-Nε-SPDB-DM4 is a drug-linker conjugate composed of a potent a tubulin inhibitor DM4 and a linker Lys-Nε-SPDB to make antibody drug conjugate (ADC)[1].
Related Catalog
Target

Maytansinoids

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References

[1]. Hans K Erickson, et al. Antibody-maytansinoid conjugates are activated in targeted cancer cells by lysosomal degradation and linker-dependent intracellular processing. Cancer Res. 2006 Apr 15;66(8):4426-33.

Molecular Formula C48H72ClN5O13S2
Molecular Weight 1026.69