Lys-Nε-SPDB-DM4

Modify Date: 2023-01-17 11:32:03

Lys-Nε-SPDB-DM4 Structure
Lys-Nε-SPDB-DM4 structure
Common Name Lys-Nε-SPDB-DM4
CAS Number 1280215-91-9 Molecular Weight 1026.69
Density N/A Boiling Point N/A
Molecular Formula C48H72ClN5O13S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Lys-Nε-SPDB-DM4


Lys-Nε-SPDB-DM4 is a drug-linker conjugate composed of a potent a tubulin inhibitor DM4 and a linker Lys-Nε-SPDB to make antibody drug conjugate (ADC)[1].

 Names

Name Lys-Nε-SPDB-DM4

 Lys-Nε-SPDB-DM4 Biological Activity

Description Lys-Nε-SPDB-DM4 is a drug-linker conjugate composed of a potent a tubulin inhibitor DM4 and a linker Lys-Nε-SPDB to make antibody drug conjugate (ADC)[1].
Related Catalog
Target

Maytansinoids

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References

[1]. Hans K Erickson, et al. Antibody-maytansinoid conjugates are activated in targeted cancer cells by lysosomal degradation and linker-dependent intracellular processing. Cancer Res. 2006 Apr 15;66(8):4426-33.

 Chemical & Physical Properties

Molecular Formula C48H72ClN5O13S2
Molecular Weight 1026.69