Name | MAK683-CH2CH2COOH |
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Description | MAK683-CH2CH2COOH binds to EED (embryonic ectoderm development protein). MAK683-CH2CH2COOH and a VHL ligand for the E3 ubiquitin ligase have been used to design PROTAC EED degrader-1 (HY-130614) and PROTAC EED degrader-2 (HY-130615)[1]. |
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Related Catalog | |
In Vitro | MAK683-CH2CH2COOH inhibits Karpas422 cells with a GI50 of 14 nM for 14 days treatment[1]. |
References |
Molecular Formula | C23H21FN6O3 |
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Molecular Weight | 448.45 |
Hazard Codes | Xi |
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