DC Chemicals Limited
China
Product Name: (S,R,S)-AHPC-C1-NH2
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Cao

2010986-20-4

2010986-20-4 structure

2010986-20-4 structure

Name: (S,R,S)-AHPC-C1-NH2
Chemical Name: (S,R,S)-AHPC-C1-NH2
CAS Number: 2010986-20-4
Molecular Formula: C₂₄H₃₃N₅O₄S
Molecular Weight: 487.61
Catalog: Signaling Pathways PROTAC E3 Ligase Ligand-Linker Conjugate
Create Date: 2021-09-14 19:50:38
Modify Date: 2024-04-07 18:16:30
(S,R,S)-AHPC-C1-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used in PROTAC technology[1].

Name	(S,R,S)-AHPC-C1-NH2

Description	(S,R,S)-AHPC-C1-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used in PROTAC technology[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate
Target	VHL
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].
References	[1]. Scheepstra M, et al. Bivalent Ligands for Protein Degradation in Drug Discovery. Comput Struct Biotechnol J. 2019;17:160-176. Published 2019 Jan 25. [2]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

Molecular Formula	C₂₄H₃₃N₅O₄S
Molecular Weight	487.61

Hazard Codes	Xi