(S,R,S)-AHPC-C1-NH2

Modify Date: 2024-04-07 18:16:30

(S,R,S)-AHPC-C1-NH2 structure	Common Name	(S,R,S)-AHPC-C1-NH2
	CAS Number	2010986-20-4	Molecular Weight	487.61
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₄H₃₃N₅O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of (S,R,S)-AHPC-C1-NH2

(S,R,S)-AHPC-C1-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used in PROTAC technology[1].

Name	(S,R,S)-AHPC-C1-NH2

Description	(S,R,S)-AHPC-C1-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used in PROTAC technology[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate
Target	VHL
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].
References	[1]. Scheepstra M, et al. Bivalent Ligands for Protein Degradation in Drug Discovery. Comput Struct Biotechnol J. 2019;17:160-176. Published 2019 Jan 25. [2]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

Molecular Formula	C₂₄H₃₃N₅O₄S
Molecular Weight	487.61

Hazard Codes	Xi

DC Chemicals Limited
China
Product Name: (S,R,S)-AHPC-C1-NH2
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Cao

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