1656261-09-4
1656261-09-4 structure
- Name: SCO-267
- Chemical Name: SCO-267
- CAS Number: 1656261-09-4
- Molecular Formula: C36H46N4O5
- Molecular Weight: 614.77
- Catalog: Signaling Pathways GPCR/G Protein GPR40
- Create Date: 2021-09-05 21:07:50
- Modify Date: 2025-08-27 09:39:48
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SCO-267 is an allosteric GPR40 full agonist. SCO-267 can be used for the research of chronic diseases including diabetes[1].
| Name | SCO-267 |
|---|
| Description | SCO-267 is an allosteric GPR40 full agonist. SCO-267 can be used for the research of chronic diseases including diabetes[1]. |
|---|---|
| Related Catalog | |
| Target |
GPR40[1] |
| In Vitro | SCO-267 (CHO cells) activates the Gαq, Gαs, and Gα12/13 pathways and β-Arrestin Recruitment. SCO-267 is allosteric with fasiglifam and an endogenous ligand[1]. |
| In Vivo | SCO-267 (1 or 10 mg/kg; p.o.) improves insulin sensitivity and exerts sustained glucose-lowering effect[1]. Animal Model: N-STZ rats[1] Dosage: 1 or 10 mg/kg Administration: P.o.; Result: Improved insulin sensitivity and exerted sustained glucose-lowering effect. |
| References |
| Molecular Formula | C36H46N4O5 |
|---|---|
| Molecular Weight | 614.77 |