1887069-10-4

1887069-10-4 structure

Name: CC-99677
Chemical Name: CC-99677
CAS Number: 1887069-10-4
Molecular Formula: C₂₂H₂₀ClN₅O₃S
Molecular Weight: 469.94
Catalog: Signaling Pathways MAPK/ERK Pathway MAPKAPK2 (MK2)
Create Date: 2021-10-23 15:56:53
Modify Date: 2024-01-09 18:43:07
CC-99677 is a potent, covalent, and irreversible inhibitor of the mitogen-activated protein (MAP) kinase-activated protein kinase-2 (MK2) pathway in both biochemical (IC50=156.3 nM) and cell based assays (EC50=89 nM). CC-99677 is extracted from patent WO2020236636, compound 1[1].

Name	CC-99677

Description	CC-99677 is a potent, covalent, and irreversible inhibitor of the mitogen-activated protein (MAP) kinase-activated protein kinase-2 (MK2) pathway in both biochemical (IC50=156.3 nM) and cell based assays (EC50=89 nM). CC-99677 is extracted from patent WO2020236636, compound 1[1].
Related Catalog	Signaling Pathways >> MAPK/ERK Pathway >> MAPKAPK2 (MK2) Research Areas >> Inflammation/Immunology
Target	MK2[1]
In Vitro	CC-99677 is a potent, covalent, and irreversible inhibitor of the mitogen-activated protein (MAP) kinase-activated protein kinase-2 (MK2) pathway in both biochemical (IC50=156.3 nM) and cell based assays (EC50=89 nM)[1].
References	[1]. WO2020236636

Molecular Formula	C₂₂H₂₀ClN₅O₃S
Molecular Weight	469.94