1383152-30-4

1383152-30-4 structure

Name: IHVR-11029
Chemical Name: (2R,3R,4R,5S)-1-[6-(2,5-Difluorophenoxy)hexyl]-2-(hydroxymethyl)-3,4,5-piperidinetriol
CAS Number: 1383152-30-4
Molecular Formula: C₁₈H₂₇F₂NO₅
Molecular Weight: 375.41
Catalog: Signaling Pathways Metabolic Enzyme/Protease Glucokinase
Create Date: 2021-12-19 14:00:03
Modify Date: 2024-01-02 18:08:08
IHVR-11029 is a small molecule inhibitor of ER α-glucosidases, with an EC50 of 0.09 μM[1].

Name	(2R,3R,4R,5S)-1-[6-(2,5-Difluorophenoxy)hexyl]-2-(hydroxymethyl)-3,4,5-piperidinetriol
Synonyms	(2R,3R,4R,5S)-1-[6-(2,5-Difluorophenoxy)hexyl]-2-(hydroxymethyl)-3,4,5-piperidinetriol 3,4,5-Piperidinetriol, 1-[6-(2,5-difluorophenoxy)hexyl]-2-(hydroxymethyl)-, (2R,3R,4R,5S)-

Description	IHVR-11029 is a small molecule inhibitor of ER α-glucosidases, with an EC50 of 0.09 μM[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Metabolic Enzyme/Protease >> Glucokinase Research Areas >> Inflammation/Immunology
Target	EC50: 0.09 μM (ER α-glucosidases)[1].
In Vitro	IHVR-11029 exhibits EC50 values of 1.3 μM, 3.3 μM and 0.75 μM for BVDV, TARV and DENV, respectively.
References	[1]. Jinhong Chang, et al. Small molecule inhibitors of ER α-glucosidases are active against multiple hemorrhagic fever viruses. Antiviral Res. 2013 Jun;98(3):432-40.