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222716-86-1

222716-86-1 structure
222716-86-1 structure
  • Name: Pegaptanib sodium
  • Chemical Name: Pegaptanib sodium
  • CAS Number: 222716-86-1
  • Molecular Formula:
  • Molecular Weight:
  • Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK VEGFR
  • Create Date: 2021-12-20 00:19:11
  • Modify Date: 2024-01-02 18:30:28
  • Pegaptanib sodium is an RNA aptamer directed against vascular endothelial growth factor (VEGF)-165. Pegaptanib could be used for the study of neovascular age-related macular degeneration (AMD) [1].

Name Pegaptanib sodium
Description Pegaptanib sodium is an RNA aptamer directed against vascular endothelial growth factor (VEGF)-165. Pegaptanib could be used for the study of neovascular age-related macular degeneration (AMD) [1].
Related Catalog
In Vitro Pegaptanib also inhibits VEGF165-mediated phosphorylation of VEGFR2 and phospholipase Cγ and inhibited VEGF165-induced calcium mobilization in human umbilical vein endothelial cells[1].
References

[1]. Eugene W M Ng, et al. Pegaptanib, a targeted anti-VEGF aptamer for ocular vascular disease. Nat Rev Drug Discov. 2006 Feb;5(2):123-32.

No Any Chemical & Physical Properties