2488761-03-9

2488761-03-9 structure

Name: Pom-8PEG
Chemical Name: Pom-8PEG
CAS Number: 2488761-03-9
Molecular Formula: C₂₉H₄₃N₃O₁₂
Molecular Weight: 625.66
Catalog: Signaling Pathways PROTAC E3 Ligase Ligand-Linker Conjugate
Create Date: 2022-03-28 01:05:50
Modify Date: 2024-01-09 19:39:31
Pom-8PEG, an E3 ligase ligand-linker conjugate, incorporates a cereblon (CRBN) ligand for the E3 ubiquitin ligase and an 8-unit PEG linker. Pom-8PEG can be used in the synthesis of PROTAC, such as IDO1 PROTAC degrader[1].

Name	Pom-8PEG

Description	Pom-8PEG, an E3 ligase ligand-linker conjugate, incorporates a cereblon (CRBN) ligand for the E3 ubiquitin ligase and an 8-unit PEG linker. Pom-8PEG can be used in the synthesis of PROTAC, such as IDO1 PROTAC degrader[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate
Target	Cereblon
References	[1]. Hu M, et al. Discovery of the first potent proteolysis targeting chimera (PROTAC) degrader of indoleamine 2,3-dioxygenase 1. Acta Pharm Sin B. 2020;10(10):1943-1953.

Molecular Formula	C₂₉H₄₃N₃O₁₂
Molecular Weight	625.66

Hazard Codes	Xi