2414285-40-6
2414285-40-6 structure
- Name: Sivopixant
- Chemical Name: Sivopixant
- CAS Number: 2414285-40-6
- Molecular Formula: C25H22ClN5O5
- Molecular Weight: 507.93
- Catalog: Signaling Pathways Membrane Transporter/Ion Channel P2X Receptor
- Create Date: 2021-12-20 16:25:16
- Modify Date: 2024-01-03 11:51:46
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Sivopixant (S-600918) is a potent and selective P2X3 receptor antagonist (P2X3 IC50=4.2 nM; P2X2/3 IC50=1100 nM). Sivopixant shows strong analgesic effect[1].
| Name | Sivopixant |
|---|
| Description | Sivopixant (S-600918) is a potent and selective P2X3 receptor antagonist (P2X3 IC50=4.2 nM; P2X2/3 IC50=1100 nM). Sivopixant shows strong analgesic effect[1]. |
|---|---|
| Related Catalog | |
| In Vivo | Sivopixant (S-600918) (i.v.;1 mg/kg) shows a longer half-life (T1/2= 10.1 hours) and a strong analgesic effect in the rat Seltzer model of allodynia (ED50=0.4 mg/kg)[1]. |
| References |
| Molecular Formula | C25H22ClN5O5 |
|---|---|
| Molecular Weight | 507.93 |