2044701-99-5

2044701-99-5 structure

Name: HDAC3 Inhibitor (Histone Deacetylase 3)
Chemical Name: HDAC3 Inhibitor
CAS Number: 2044701-99-5
Molecular Formula: C₂₀H₂₃N₃O₂
Molecular Weight: 337.42
Catalog: Signaling Pathways Cell Cycle/DNA Damage HDAC
Create Date: 2022-02-08 15:25:53
Modify Date: 2024-01-14 12:24:33
HDAC3-IN-1 (compound 5) is a potent and selective HDAC3 inhibitor, with an IC50 of 5.96 nM[1].

Name	HDAC3 Inhibitor

Description	HDAC3-IN-1 (compound 5) is a potent and selective HDAC3 inhibitor, with an IC50 of 5.96 nM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> HDAC Signaling Pathways >> Epigenetics >> HDAC
Target	HDAC3:5.96 ± 0.0 nM (IC50) HDAC1:36.4 ± 0.2 nM (IC50) HDAC2:89.9 ± 0.7 nM (IC50)
References	[1]. Moreno-Yruela C, Olsen CA. Determination of Slow-Binding HDAC Inhibitor Potency and Subclass Selectivity. ACS Med Chem Lett. 2022 Mar 16;13(5):779-785.