HDAC3 Inhibitor (Histone Deacetylase 3)

Modify Date: 2024-01-14 12:24:33

HDAC3 Inhibitor (Histone Deacetylase 3) structure	Common Name	HDAC3 Inhibitor (Histone Deacetylase 3)
	CAS Number	2044701-99-5	Molecular Weight	337.42
	Density	1.140±0.06 g/cm3(Predicted)	Boiling Point	562.5±50.0 °C(Predicted)
	Molecular Formula	C₂₀H₂₃N₃O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of HDAC3 Inhibitor (Histone Deacetylase 3)

HDAC3-IN-1 (compound 5) is a potent and selective HDAC3 inhibitor, with an IC50 of 5.96 nM[1].

Name	HDAC3 Inhibitor

Description	HDAC3-IN-1 (compound 5) is a potent and selective HDAC3 inhibitor, with an IC50 of 5.96 nM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> HDAC Signaling Pathways >> Epigenetics >> HDAC
Target	HDAC3:5.96 ± 0.0 nM (IC50) HDAC1:36.4 ± 0.2 nM (IC50) HDAC2:89.9 ± 0.7 nM (IC50)
References	[1]. Moreno-Yruela C, Olsen CA. Determination of Slow-Binding HDAC Inhibitor Potency and Subclass Selectivity. ACS Med Chem Lett. 2022 Mar 16;13(5):779-785.

Density	1.140±0.06 g/cm3(Predicted)
Boiling Point	562.5±50.0 °C(Predicted)
Molecular Formula	C₂₀H₂₃N₃O₂
Molecular Weight	337.42

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