1354448-60-4
1354448-60-4 structure
- Name: KH-CB20
- Chemical Name: KH-CB20
- CAS Number: 1354448-60-4
- Molecular Formula: C15H13Cl2N3O2
- Molecular Weight: 338.19
- Catalog: Signaling Pathways Cell Cycle/DNA Damage CDK
- Create Date: 2022-02-20 14:42:39
- Modify Date: 2024-01-10 12:17:48
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KH-CB20, an E/Z mixture, is a potent and selective inhibitor of CLK1, with an IC50 of 16.5 nM. KH-CB20 also can inhibits DYRK1A (IC50=57.8 nM) and CLK3 (IC50=488 nM)[1].
| Name | KH-CB20 |
|---|
| Description | KH-CB20, an E/Z mixture, is a potent and selective inhibitor of CLK1, with an IC50 of 16.5 nM. KH-CB20 also can inhibits DYRK1A (IC50=57.8 nM) and CLK3 (IC50=488 nM)[1]. |
|---|---|
| Related Catalog | |
| Target |
CLK1:16.5 nM (IC50) DYRK1A:57.8 nM (IC50) CLK3:488 nM (IC50) |
| In Vitro | KH-CB20 shows selectivity for CLK1 (IC50=16.5 nM) over DYRK1A (IC50=57.8 nM) and CLK3 (IC50=488 nM)[1]. |
| References |
| Molecular Formula | C15H13Cl2N3O2 |
|---|---|
| Molecular Weight | 338.19 |
| Hazard Codes | Xi |
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