KH-CB20
Modify Date: 2024-01-10 12:17:48
KH-CB20 structure
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Common Name | KH-CB20 | ||
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| CAS Number | 1354448-60-4 | Molecular Weight | 338.19 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C15H13Cl2N3O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of KH-CB20KH-CB20, an E/Z mixture, is a potent and selective inhibitor of CLK1, with an IC50 of 16.5 nM. KH-CB20 also can inhibits DYRK1A (IC50=57.8 nM) and CLK3 (IC50=488 nM)[1]. |
| Name | KH-CB20 |
|---|
| Description | KH-CB20, an E/Z mixture, is a potent and selective inhibitor of CLK1, with an IC50 of 16.5 nM. KH-CB20 also can inhibits DYRK1A (IC50=57.8 nM) and CLK3 (IC50=488 nM)[1]. |
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| Related Catalog | |
| Target |
CLK1:16.5 nM (IC50) DYRK1A:57.8 nM (IC50) CLK3:488 nM (IC50) |
| In Vitro | KH-CB20 shows selectivity for CLK1 (IC50=16.5 nM) over DYRK1A (IC50=57.8 nM) and CLK3 (IC50=488 nM)[1]. |
| References |
| Molecular Formula | C15H13Cl2N3O2 |
|---|---|
| Molecular Weight | 338.19 |
| Hazard Codes | Xi |
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