2574456-10-1

2574456-10-1 structure
2574456-10-1 structure
  • Name: TNK2-IN-1
  • Chemical Name: TNK2-IN-1
  • CAS Number: 2574456-10-1
  • Molecular Formula: C23H24N6O2
  • Molecular Weight: 416.48
  • Catalog: Signaling Pathways Metabolic Enzyme/Protease Tyrosinase
  • Create Date: 2022-02-21 11:30:33
  • Modify Date: 2024-01-18 22:42:36
  • TNK2-IN-1 is a TNK2 inhibitor. TNK2-IN-1 has an IC50 of 224 nM for TNK2. TNK2-IN-1 can be used for the research of cancer[1].

Name TNK2-IN-1
Description TNK2-IN-1 is a TNK2 inhibitor. TNK2-IN-1 has an IC50 of 224 nM for TNK2. TNK2-IN-1 can be used for the research of cancer[1].
Related Catalog
Target

TNK2:224 nM (IC50)

In Vitro TNK2-IN-1 (compound 21) has an EC50 of 0.15 μM for cell viability of Ba/F3 cells expressing TNK2 D163E[1].
References

[1]. Li Z, et al. Discovery of a series of benzopyrimidodiazepinone TNK2 inhibitors via scaffold morphing. Bioorg Med Chem Lett. 2020 Oct 1;30(19):127456.

Molecular Formula C23H24N6O2
Molecular Weight 416.48