TNK2-IN-1

Modify Date: 2025-08-23 20:10:13

TNK2-IN-1 Structure
TNK2-IN-1 structure
Common Name TNK2-IN-1
CAS Number 2574456-10-1 Molecular Weight 416.48
Density N/A Boiling Point N/A
Molecular Formula C23H24N6O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TNK2-IN-1


TNK2-IN-1 is a TNK2 inhibitor. TNK2-IN-1 has an IC50 of 224 nM for TNK2. TNK2-IN-1 can be used for the research of cancer[1].

 Names

Name TNK2-IN-1

 TNK2-IN-1 Biological Activity

Description TNK2-IN-1 is a TNK2 inhibitor. TNK2-IN-1 has an IC50 of 224 nM for TNK2. TNK2-IN-1 can be used for the research of cancer[1].
Related Catalog
Target

TNK2:224 nM (IC50)

In Vitro TNK2-IN-1 (compound 21) has an EC50 of 0.15 μM for cell viability of Ba/F3 cells expressing TNK2 D163E[1].
References

[1]. Li Z, et al. Discovery of a series of benzopyrimidodiazepinone TNK2 inhibitors via scaffold morphing. Bioorg Med Chem Lett. 2020 Oct 1;30(19):127456.

 Chemical & Physical Properties

Molecular Formula C23H24N6O2
Molecular Weight 416.48
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