1303513-80-5

1303513-80-5 structure

Name: Izilendustat hydrochloride
Chemical Name: Izilendustat hydrochloride
CAS Number: 1303513-80-5
Molecular Formula: C₂₂H₂₉Cl₂N₃O₄
Molecular Weight: 470.39
Catalog: Signaling Pathways Metabolic Enzyme/Protease HIF/HIF Prolyl-Hydroxylase
Create Date: 2022-03-23 19:27:33
Modify Date: 2024-01-10 21:46:02
Izilendustat (hydrochloride) is a potent inhibitor of prolyl hydroxylase which stabilizes hypoxia inducible factor- 1 alpha (HIF- lα), as well as hypoxia inducible factor-2 (HIF-2). Izilendustat (hydrochloride) has the potential for the research of HIF- lα related diseases including Peripheral Vascular Disease (PVD), Coronary Artery Disease (CAD), heart failure, ischemia, anemia, colitis, and other inflammatory bowel diseases (extracted from patent WO2011057115A1/WO2011057112A1/WO2011057121A1)[1][2][3].

Name	Izilendustat hydrochloride

Description	Izilendustat (hydrochloride) is a potent inhibitor of prolyl hydroxylase which stabilizes hypoxia inducible factor- 1 alpha (HIF- lα), as well as hypoxia inducible factor-2 (HIF-2). Izilendustat (hydrochloride) has the potential for the research of HIF- lα related diseases including Peripheral Vascular Disease (PVD), Coronary Artery Disease (CAD), heart failure, ischemia, anemia, colitis, and other inflammatory bowel diseases (extracted from patent WO2011057115A1/WO2011057112A1/WO2011057121A1)[1][2][3].
Related Catalog	Research Areas >> Cancer Research Areas >> Inflammation/Immunology Signaling Pathways >> Metabolic Enzyme/Protease >> HIF/HIF Prolyl-Hydroxylase
Target	prolyl hydroxylase[1]
References	[1]. Joseph H, et al. Prolyl hydroxylase inhibitors. Patent WO2011057115A1. [2]. Robert Shalwitz, et al. Methods for increasing the stabilization of hypoxia inducible factor-1 alpha. Patent WO2011057112A1. [3]. Joseph H, et al. Compositions and methods for treating colitis. Patent WO2011057121A1.

Molecular Formula	C₂₂H₂₉Cl₂N₃O₄
Molecular Weight	470.39