1420815-74-2

1420815-74-2 structure

Name: L-Glutamic acid-13C5,d5,15N
Chemical Name: L-Glutamic acid-13C5,d5,15N
CAS Number: 1420815-74-2
Molecular Formula: ₁₃C₅H₄D₅₁₅NO₄
Molecular Weight: 158.12
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2022-03-25 18:09:24
Modify Date: 2024-01-05 10:40:24
L-Glutamic acid-13C5,d5,15N is the deuterium, 13C-, and 15-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.

Name	L-Glutamic acid-13C5,d5,15N

Description	L-Glutamic acid-13C5,d5,15N is the deuterium, 13C-, and 15-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.
Related Catalog	Signaling Pathways >> Neuronal Signaling >> iGluR Signaling Pathways >> Apoptosis >> Apoptosis Signaling Pathways >> Apoptosis >> Ferroptosis Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Molecular Formula	₁₃C₅H₄D₅₁₅NO₄
Molecular Weight	158.12