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1787787-60-3

1787787-60-3 structure
1787787-60-3 structure
  • Name: NLRP3/AIM2-IN-3
  • Chemical Name: NLRP3/AIM2-IN-3
  • CAS Number: 1787787-60-3
  • Molecular Formula: C16H14N2O2
  • Molecular Weight: 266.29
  • Catalog: Research Areas Inflammation/Immunology
  • Create Date: 2022-03-28 19:13:56
  • Modify Date: 2024-01-04 12:54:08
  • NLRP3/AIM2-IN-3 is a unique molecule that inhibits the activation of < b > NLRP3 < / b > and < b > AIM2 < / b > inflammatory bodies and has species differences. Its < b > IC < sub > 50 < / sub > < / b > value is 0.077 ± 0.008 μ M。

Name NLRP3/AIM2-IN-3
Description NLRP3/AIM2-IN-3 is a unique molecule that inhibits the activation of < b > NLRP3 < / b > and < b > AIM2 < / b > inflammatory bodies and has species differences. Its < b > IC < sub > 50 < / sub > < / b > value is 0.077 ± 0.008 μ M。
Related Catalog
Target

 inhibitory activity against NLRP3 and AIM2:0.077±0.00 μM (IC50)

References

[1]. Jiao Y, et al. Discovery of a novel and potent inhibitor with differential species-specific effects against NLRP3 and AIM2 inflammasome-dependent pyroptosis. Eur J Med Chem. 2022 Feb 11;232:114194.

Molecular Formula C16H14N2O2
Molecular Weight 266.29