NLRP3/AIM2-IN-3

Modify Date: 2024-01-04 12:54:08

NLRP3/AIM2-IN-3 Structure
NLRP3/AIM2-IN-3 structure
Common Name NLRP3/AIM2-IN-3
CAS Number 1787787-60-3 Molecular Weight 266.29
Density N/A Boiling Point N/A
Molecular Formula C16H14N2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NLRP3/AIM2-IN-3


NLRP3/AIM2-IN-3 is a unique molecule that inhibits the activation of < b > NLRP3 < / b > and < b > AIM2 < / b > inflammatory bodies and has species differences. Its < b > IC < sub > 50 < / sub > < / b > value is 0.077 ± 0.008 μ M。

 Names

Name NLRP3/AIM2-IN-3

 NLRP3/AIM2-IN-3 Biological Activity

Description NLRP3/AIM2-IN-3 is a unique molecule that inhibits the activation of < b > NLRP3 < / b > and < b > AIM2 < / b > inflammatory bodies and has species differences. Its < b > IC < sub > 50 < / sub > < / b > value is 0.077 ± 0.008 μ M。
Related Catalog
Target

 inhibitory activity against NLRP3 and AIM2:0.077±0.00 μM (IC50)

References

[1]. Jiao Y, et al. Discovery of a novel and potent inhibitor with differential species-specific effects against NLRP3 and AIM2 inflammasome-dependent pyroptosis. Eur J Med Chem. 2022 Feb 11;232:114194.

 Chemical & Physical Properties

Molecular Formula C16H14N2O2
Molecular Weight 266.29