166977-57-7

166977-57-7 structure

Name: AGN 192870
Chemical Name: AGN 192870
CAS Number: 166977-57-7
Molecular Formula: C₂₇H₂₂O₂
Molecular Weight: 378.46
Catalog: Signaling Pathways Metabolic Enzyme/Protease RAR/RXR
Create Date: 2022-06-30 21:34:54
Modify Date: 2024-01-12 17:43:51
AGN 192870 is a RAR neutral antagonist with Kds of 147, 33, and 42 nM for RARα, RARβ, and RARγ, respectively. AGN 192870 shows IC50s of 87 and 32 nM for RARαand RARγ, respectively. AGN 192870 shows RARβ partial agonism[1].

Name	AGN 192870

Description	AGN 192870 is a RAR neutral antagonist with Kds of 147, 33, and 42 nM for RARα, RARβ, and RARγ, respectively. AGN 192870 shows IC50s of 87 and 32 nM for RARαand RARγ, respectively. AGN 192870 shows RARβ partial agonism[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Metabolic Enzyme/Protease >> RAR/RXR
References	[1]. Klein ES, et al. Identification and functional separation of retinoic acid receptor neutral antagonists and inverse agonists. J Biol Chem. 1996;271(37):22692-22696.

Molecular Formula	C₂₇H₂₂O₂
Molecular Weight	378.46