AGN 192870

Modify Date: 2024-01-12 17:43:51

AGN 192870 Structure
AGN 192870 structure
Common Name AGN 192870
CAS Number 166977-57-7 Molecular Weight 378.46
Density N/A Boiling Point N/A
Molecular Formula C27H22O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of AGN 192870


AGN 192870 is a RAR neutral antagonist with Kds of 147, 33, and 42 nM for RARα, RARβ, and RARγ, respectively. AGN 192870 shows IC50s of 87 and 32 nM for RARαand RARγ, respectively. AGN 192870 shows RARβ partial agonism[1].

 Names

Name AGN 192870

 AGN 192870 Biological Activity

Description AGN 192870 is a RAR neutral antagonist with Kds of 147, 33, and 42 nM for RARα, RARβ, and RARγ, respectively. AGN 192870 shows IC50s of 87 and 32 nM for RARαand RARγ, respectively. AGN 192870 shows RARβ partial agonism[1].
Related Catalog
References

[1]. Klein ES, et al. Identification and functional separation of retinoic acid receptor neutral antagonists and inverse agonists. J Biol Chem. 1996;271(37):22692-22696.

 Chemical & Physical Properties

Molecular Formula C27H22O2
Molecular Weight 378.46