2639542-22-4

2639542-22-4 structure
2639542-22-4 structure
  • Name: CDK5-IN-2
  • Chemical Name: CDK5-IN-2
  • CAS Number: 2639542-22-4
  • Molecular Formula: C29H28FN5O
  • Molecular Weight: 481.56
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage CDK
  • Create Date: 2022-04-29 18:28:55
  • Modify Date: 2024-01-02 18:49:17
  • CDK5-IN-2 (compound 15) is a highly selective CDK5 inhibitor with IC50s of 0.2 and 23 for CDK5/p25 and CDK2/CycA, respectively[1].

Name CDK5-IN-2
Description CDK5-IN-2 (compound 15) is a highly selective CDK5 inhibitor with IC50s of 0.2 and 23 for CDK5/p25 and CDK2/CycA, respectively[1].
Related Catalog
Target

Cdk5/p25:0.2 nM (IC50)

CDK2/CycA:23 nM (IC50)

References

[1]. Daniels MH, et al. Discovery and Optimization of Highly Selective Inhibitors of CDK5. J Med Chem. 2022;65(4):3575-3596.

Molecular Formula C29H28FN5O
Molecular Weight 481.56
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.