Top Suppliers:I want be here
  • DC Chemicals Limited
  • China
  • Product Name: MI-389
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao
Related CAS#:
2222635-92-7 54328-43-7
1410737-35-7 1934302-23-4
1709863-43-3 908027-55-4
1303607-07-9 1415340-63-4
1628317-18-9 1857417-10-7
2137562-01-5 1158522-08-7
940364-43-2 134104-43-1
131615-57-1 6906-52-1
930439-75-1 1018584-77-4
1375289-11-4 849349-65-1

2222635-92-7

2222635-92-7 structure
2222635-92-7 structure
  • Name: MI-389
  • Chemical Name: MI-389
  • CAS Number: 2222635-92-7
  • Molecular Formula: C35H35FN6O6
  • Molecular Weight: 654.69
  • Create Date: 2022-05-30 13:36:53
  • Modify Date: 2024-01-10 11:11:11
  • MI-389 is a PROTAC translation termination factor GSPT1 degrader. MI-389 disrupts a target that is a shared dependency in different AML and ALL cell lines, and that MI-389 action is dependent on the CRL4CRBN E3 ligase[1].
Name MI-389
Description MI-389 is a PROTAC translation termination factor GSPT1 degrader. MI-389 disrupts a target that is a shared dependency in different AML and ALL cell lines, and that MI-389 action is dependent on the CRL4CRBN E3 ligase[1].
Related Catalog
Target

Cereblon

References

[1]. Ishoey M, et al. Translation Termination Factor GSPT1 Is a Phenotypically Relevant Off-Target of Heterobifunctional Phthalimide Degraders. ACS Chem Biol. 2018;13(3):553-560.

Molecular Formula C35H35FN6O6
Molecular Weight 654.69

Chemsrc provides CAS#:2222635-92-7 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 2222635-92-7 | Chemsrc address: https://m.chemsrc.com/en/baike/1705435.html

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved