2222635-92-7
2222635-92-7 structure
- Name: MI-389
- Chemical Name: MI-389
- CAS Number: 2222635-92-7
- Molecular Formula: C35H35FN6O6
- Molecular Weight: 654.69
- Create Date: 2022-05-30 13:36:53
- Modify Date: 2024-01-10 11:11:11
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MI-389 is a PROTAC translation termination factor GSPT1 degrader. MI-389 disrupts a target that is a shared dependency in different AML and ALL cell lines, and that MI-389 action is dependent on the CRL4CRBN E3 ligase[1].
| Name | MI-389 |
|---|
| Description | MI-389 is a PROTAC translation termination factor GSPT1 degrader. MI-389 disrupts a target that is a shared dependency in different AML and ALL cell lines, and that MI-389 action is dependent on the CRL4CRBN E3 ligase[1]. |
|---|---|
| Related Catalog | |
| Target |
Cereblon |
| References |
| Molecular Formula | C35H35FN6O6 |
|---|---|
| Molecular Weight | 654.69 |