2645409-78-3

2645409-78-3 structure
2645409-78-3 structure
  • Name: RMS-07
  • Chemical Name: RMS-07
  • CAS Number: 2645409-78-3
  • Molecular Formula: C35H40N8O2
  • Molecular Weight: 604.74
  • Create Date: 2022-05-17 17:49:12
  • Modify Date: 2025-08-27 08:18:19
  • RMS-07 is a covalent Monopolar Spindle Kinase 1 (MPS1/TTK) inhibitor, with an apparent IC50 of 13.1 nM. RMS-07 targets a poorly conserved cysteine in the kinase's hinge region[1].

Name RMS-07
Description RMS-07 is a covalent Monopolar Spindle Kinase 1 (MPS1/TTK) inhibitor, with an apparent IC50 of 13.1 nM. RMS-07 targets a poorly conserved cysteine in the kinase's hinge region[1].
Related Catalog
Target

IC50:13.1 nM (Monopolar Spindle Kinase 1 (MPS1/TTK)).

References

[1]. Ricardo A M Serafim, et al. Development of the First Covalent Monopolar Spindle Kinase 1 (MPS1/TTK) Inhibitor. J Med Chem. 2022 Feb 24;65(4):3173-3192.

Molecular Formula C35H40N8O2
Molecular Weight 604.74
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