788799-13-3

788799-13-3 structure

Name: AFP-07 free acid
Chemical Name: (5Z)-5-[(3aR,4R,5R,6aS)-3,3-difluoro-5-hydroxy-4-[(E,3S,4S)-3-hydroxy-4-methylnon-1-en-6-ynyl]-4,5,6,6a-tetrahydro-3aH-cyclopenta[b]furan-2-ylidene]pentanoic acid
CAS Number: 788799-13-3
Molecular Formula: C₂₂H₃₀F₂O₅
Molecular Weight: 412.467
Create Date: 2016-04-24 10:55:00
Modify Date: 2024-08-22 23:55:11
AFP 07 free acid is a 7,7-difluoroprostacyclin derivative that acts as a selective and highly potent agonist for the IP receptor. Prostaglandin I2 is an unstable prostanoid which, through the ‘I prostanoid’ (IP) receptor, inhibits platelet aggregation and promotes vasodilatation in pulmonary vascular beds.

Name	(5Z)-5-[(3aR,4R,5R,6aS)-3,3-difluoro-5-hydroxy-4-[(E,3S,4S)-3-hydroxy-4-methylnon-1-en-6-ynyl]-4,5,6,6a-tetrahydro-3aH-cyclopenta[b]furan-2-ylidene]pentanoic acid
Synonyms	AFP-07 free acid (5Z)-5-{(3aR,4R,5R,6aS)-3,3-Difluoro-5-hydroxy-4-[(1E,3S,4S)-3-hydroxy-4-methyl-1-nonen-6-yn-1-yl]hexahydro-2H-cyclopenta[b]furan-2-ylidene}pentanoic acid UNII-69PPR64XJA (5Z)-5-{(3aR,4R,5R,6aS)-3,3-Difluoro-5-hydroxy-4-[(1E,3S,4S)-3-hydroxy-4-methyl-1-nonen-6-yn-1-yl]hexahydro-2H-cyclopenta[b]furan-2-ylidene}pentanoic acid (non-preferred name)