2361742-30-3

2361742-30-3 structure

Name: VPC-70619
Chemical Name: VPC-70619
CAS Number: 2361742-30-3
Molecular Formula: C₁₆H₈ClF₃N₄O
Molecular Weight: 364.71
Create Date: 2022-05-05 19:30:28
Modify Date: 2024-01-09 17:28:17
VPC-70619 is a potent, orally active N-Myc inhibitor. VPC-70619 blocks the N-Myc-Max heterocomplex from binding to DNA E-boxes and demonstrated strong inhibition activity against N-Myc-dependent cell lines as well as high bioavailability in both oral and intraperitoneal administration[1].

Name	VPC-70619

Description	VPC-70619 is a potent, orally active N-Myc inhibitor. VPC-70619 blocks the N-Myc-Max heterocomplex from binding to DNA E-boxes and demonstrated strong inhibition activity against N-Myc-dependent cell lines as well as high bioavailability in both oral and intraperitoneal administration[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Apoptosis >> c-Myc
References	[1]. Ton AT, et al. Development of VPC-70619, a Small-Molecule N-Myc Inhibitor as a Potential Therapy for Neuroendocrine Prostate Cancer. Int J Mol Sci. 2022;23(5):2588. Published 2022 Feb 26.

Molecular Formula	C₁₆H₈ClF₃N₄O
Molecular Weight	364.71