VPC-70619

Modify Date: 2024-01-09 17:28:17

VPC-70619 Structure
VPC-70619 structure
Common Name VPC-70619
CAS Number 2361742-30-3 Molecular Weight 364.71
Density N/A Boiling Point N/A
Molecular Formula C16H8ClF3N4O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of VPC-70619


VPC-70619 is a potent, orally active N-Myc inhibitor. VPC-70619 blocks the N-Myc-Max heterocomplex from binding to DNA E-boxes and demonstrated strong inhibition activity against N-Myc-dependent cell lines as well as high bioavailability in both oral and intraperitoneal administration[1].

 Names

Name VPC-70619

 VPC-70619 Biological Activity

Description VPC-70619 is a potent, orally active N-Myc inhibitor. VPC-70619 blocks the N-Myc-Max heterocomplex from binding to DNA E-boxes and demonstrated strong inhibition activity against N-Myc-dependent cell lines as well as high bioavailability in both oral and intraperitoneal administration[1].
Related Catalog
References

[1]. Ton AT, et al. Development of VPC-70619, a Small-Molecule N-Myc Inhibitor as a Potential Therapy for Neuroendocrine Prostate Cancer. Int J Mol Sci. 2022;23(5):2588. Published 2022 Feb 26.

 Chemical & Physical Properties

Molecular Formula C16H8ClF3N4O
Molecular Weight 364.71
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