Name | Autotaxin-IN-13 |
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Description | Autotaxin-IN-13 ( ATX-i) is a highly potent, selective Autotaxin inhibitor with IC50 of 6 nM.Autotaxin showed sufficient oral bioavailability and low plasma clearance in vivo as well as a suitable half-life to allow for bid or food admix dosing. |
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References | 1. Daniel Hunziker, et al. Front Pharmacol. 2022 Jan 18;12:699535. |
Molecular Formula | C22H20F3N5O4 |
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Molecular Weight | 475.428 |