Shanghai Nianxing Industrial Co., Ltd
China
Product Name: ATG7-IN-2
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Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

2226227-75-2

2226227-75-2 structure

2226227-75-2 structure

Name: ATG7-IN-2
Chemical Name: ATG7-IN-2
CAS Number: 2226227-75-2
Molecular Formula: C₁₁H₁₆N₆O₇S
Molecular Weight: 376.35
Catalog: Signaling Pathways Autophagy Autophagy
Create Date: 2022-07-10 23:09:17
Modify Date: 2024-01-28 13:12:30
ATG7-IN-2 (compound 1) is a potent ATG7 inhibitor, with an IC50 of 0.089 μM. ATG7-IN-2 inhibits autophagy marker LC3B[1].

Name	ATG7-IN-2

Description	ATG7-IN-2 (compound 1) is a potent ATG7 inhibitor, with an IC50 of 0.089 μM. ATG7-IN-2 inhibits autophagy marker LC3B[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Autophagy >> Autophagy
Target	IC50: 0.089 ± 0.036 μM (ATG7), 0.335 ± 0.049 μM (Thioester), 2.6 μM (LC3B)[1]
References	[1]. Huang SC, et al. Discovery and optimization of pyrazolopyrimidine sulfamates as ATG7 inhibitors. Bioorg Med Chem. 2020 Oct 1;28(19):115681.

Molecular Formula	C₁₁H₁₆N₆O₇S
Molecular Weight	376.35