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2691936-89-5

2691936-89-5 structure

2691936-89-5 structure

Name: ATX inhibitor 21
Chemical Name: ATX inhibitor 21
CAS Number: 2691936-89-5
Molecular Formula: C₂₆H₂₅F₂N₅O₂S
Molecular Weight: 509.57
Catalog: Signaling Pathways Metabolic Enzyme/Protease Phosphodiesterase (PDE)
Create Date: 2022-07-02 20:24:29
Modify Date: 2024-01-13 02:32:45
ATX inhibitor 21 (compound 8) is a potent ATX (autotaxin) inhibitor, with an IC50 of 3490 nM[1].

Name	ATX inhibitor 21

Description	ATX inhibitor 21 (compound 8) is a potent ATX (autotaxin) inhibitor, with an IC50 of 3490 nM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE)
Target	Autotaxin:3490 ± 170 nM (IC50)
References	[1]. Jia F, et al. Structure-based linker exploration: Discovery of 1-ethyl-1H-indole analogs as novel ATX inhibitors. Bioorg Med Chem. 2020 Nov 15;28(22):115795.

Molecular Formula	C₂₆H₂₅F₂N₅O₂S
Molecular Weight	509.57

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