ATX inhibitor 21

Modify Date: 2024-01-13 02:32:45

ATX inhibitor 21 Structure
ATX inhibitor 21 structure
Common Name ATX inhibitor 21
CAS Number 2691936-89-5 Molecular Weight 509.57
Density N/A Boiling Point N/A
Molecular Formula C26H25F2N5O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ATX inhibitor 21


ATX inhibitor 21 (compound 8) is a potent ATX (autotaxin) inhibitor, with an IC50 of 3490 nM[1].

 Names

Name ATX inhibitor 21

 ATX inhibitor 21 Biological Activity

Description ATX inhibitor 21 (compound 8) is a potent ATX (autotaxin) inhibitor, with an IC50 of 3490 nM[1].
Related Catalog
Target

Autotaxin:3490 ± 170 nM (IC50)

References

[1]. Jia F, et al. Structure-based linker exploration: Discovery of 1-ethyl-1H-indole analogs as novel ATX inhibitors. Bioorg Med Chem. 2020 Nov 15;28(22):115795.

 Chemical & Physical Properties

Molecular Formula C26H25F2N5O2S
Molecular Weight 509.57